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citalopram and meperidine both equally maximize serotonin stages. Use Caution/observe. mix may maximize hazard of serotonin syndrome or neuroleptic malignant syndrome-like reactions.

idea - To select multiple things in an inventory box, press the Ctrl/Command key and click on Just about every product you want to pick out. If you can't find more than only one item in a list box, then the PDF author made the sector to simply accept only just one reaction.

Risk of opioid dependancy, abuse, and misuse, which can lead to overdose and Demise; evaluate Every single client’s danger before prescribing and reassess all clients regularly for improvement of these behaviors and problems

Caution is additionally needed in people with acute alcoholism, elevated intracranial pressure, or heritage of convulsive disorders, existing hypotension as it might decrease the hypertension even more, myasthenia gravis.

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utilization of a small graduated syringe is suggested for that correct administration of dosages in little ones. during the absence of graduated syringes, the answer need to be diluted with Water for Injections ahead of measuring the dose.

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Paediatric populace the standard solitary dose is 0.5 to 2mg/kg physique excess weight by intramuscular injection. If necessary, this dose may very well be repeated, enabling no less than four hours between doses.

though severe, lifetime-threatening, or lethal respiratory despair can come about Anytime all through therapy, the danger is best through the initiation of therapy or pursuing a dosage raise; keep an eye on patients carefully for respiratory despair, Specially in the first 24-seventy two hours of initiating therapy with and pursuing dosage increases; to reduce danger of respiratory melancholy, suitable dosing and titration are critical; overestimating dosage when changing patients from A further opioid products can lead to a deadly overdose with the primary dose

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in just 14 times of taking MAO inhibitors; if linezolid or IV methylene blue (MAOIs) has to be administered, discontinue serotonergic drug instantly and check for CNS toxicity; may resume 24 hr after very last linezolid or methylene blue dose, or soon after 2 weeks of monitoring, whichever will come first

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